| An ELISA for the determination of oligomerized Mannan-binding lectin (MBL) in human serum or heparin plasma
MBL – a key test in the assessment of primary immunodeficiency
Mannan-binding lectin (MBL) is an important component of the innate immune system. However, in at least 12% of the average Caucasian population, the circulating level of functional MBL is insufficient. This makes MBL deficiency by far the most common primary immunodeficiency.
Clinical application
Deficiency of MBL has been shown to increase the overall susceptibility to infectious diseases and to predispose to greater disease severity; hence especially early and aggressive treatment with antibiotics can be required in risk patients such as those on cancer chemotherapy or immunosuppressant treatment.
MBL is a key test parameter in:
- Patients with a suspected primary immunodeficiency
- Children with recurrent infections
- Adults with recurrent, severe & persistent infections
- Immunosuppressed patients
- Cancer chemotherapy
- Transplantation
- Patients with cystic fibrosis
* For in-vitro diagnostic use in selected countries. Please visit www.bioporto.com for availability in your country.
Vendor Product Page:
RUO Kit
CE IVD Kit | 
