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> > > Scl-70-directed antibody EIA Kit

Scl-70-directed antibody EIA Kit

Scl-70-directed antibody EIA Kit
General Information
VendorIBL-America
ItemScl-70-directed antibody EIA Kit
Catalog NumberORG 512
Size1 x 96
Regulatory Status510k Cleared
PricingInquire
Product Description
Progressive systemic scleroderma is an autoimmune disorder of the connective tissue leading to slowly progressive fibrosis and later to sclerosis. Subsequently patients suffering from scleroderma develop tight skin and manifest involvement of the heart, kidneys and lungs. Scl-70 antibodies are directed against the enzyme DNA Topoisomerase I and are highly specific for scleroderma (> 90%). Patients with anti-Scl-70 antibodies are more likely to have facial skin involvement and tend to develop manifestation of the heart, kidneys and lungs in comparison with anti-Scl-70 antibodies negative scleroderma patients.
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